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Mosapride

Tus Txheej Txheem: Nqe lus piav qhia: Mosapride yog ib tus neeg ua hauj lwm hauv gastroprokinetic uas ua raws li kev xaiv 5HT4 agonist. Qhov loj lub cev metabolite ntawm mosapride, hu ua M1, ntxiv thiab ua raws li ib tug 5HT3 antagonist. uas accelerates gastric muab txhua txhua lub sij hawm ntawm txoj hnyuv hauv tib neeg, ...

  • Nta & Specification

    P NPE NPE

    Mosapride

    CAS Naj Npawb:

    112885-41-3

    Qhia tawm

    4-amino-5-chloro-2-ethoxy-N - [[4 - [(4-fluorophenyl) methyl] morpholin-2-yl] methyl] benzamide

    Mis :

    C21H25ClFN3O3

    Molecular phaus :

    421.89300

    PSA:

    76.82000

    LogP:

    4.00080

    Qauv :
    图片 12.png

    Kev piav qhia :
    Mosapride yog ib tug neeg sawv cev ntawm tus kws lij choj uas ua tus xaiv 5HT4 agonist. Qhov loj lub cev metabolite ntawm mosapride, hu ua M1, ntxiv thiab ua raws li ib tug 5HT3 antagonist. uas accelerates gastric muab nchuav tag nrho tag nrho ntawm txoj hnyuv hauv tib neeg, thiab yog siv rau kev kho mob ntawm gastritis, gastroesophageal reflux kab mob, dyspepsia thiab irritable plob tsis so tswj syndrome. Nws raug nquahu kom tau noj rau ntawm lub plab (xws li tsawg kawg yog ib teev ua ntej noj mov lossis ob teev tom qab zaub mov).
    Ntxiv nrog rau nws cov khoom prokinetic, mosapride kuj exerts anti-inflammatory teebmeem rau txoj hnyuv huam uas yuav ua tau rau qee yam ntawm nws cov kev kho mob. Mosapride kuj txhawb nqa cov paj hlwb hauv lub plab nyhuv uas yuav pab tau cov kab mob hauv plab. Tus kab mob neurogenesis yog vim li cas mosapride cov nyhuv rau 5-HT4 reseptor uas nws ua raws li kev lag luam.
    Nws cov kev mob tshwm sim muaj xws li lub qhov ncauj qhuav, mob plab, kiv taub hau, mob taub hau, pw tsis tsaug zog, mob siab, xeev siab, zawv plab thiab qee zaum cem quav. Tsis zoo li lwm tus neeg sawv cev ntawm cov tshuaj prokinetic, mosapride muaj cov nyhuv me me rau cov kua qaub, tsis muaj teebmeem rau cov kab mob hauv HERV, thiab tsis muaj teebmeem kev mob plawv uas tuaj yeem kuaj tau rau tib neeg. Vim yog lub pharmacokinetics ntawm mosapride, nws yuav siv sij hawm 1,000-3,000 zaus ntawm cov tshuaj kho kom haum rau cov teebmeem plawv.

    Tshwm Sim & Lub Cev Lub Cev:

    Dawb rau Tawm-Dawb Crystalline Khoom

    Ceev:

    1.272 g / cm3

    Melting Point:

    151-153ºC

    Kub Point:

    549.2ºC ntawm 760 hliHg

    Flash Point:

    286ºC

    Refractive Index:

    1.584

    Vapor Siab:

    4.11E-12mmHg ntawm 25 ° C

    RTECS:

    LW9100000

    Cov Kev Kawm Hwm:

    8

    Lus Qhia Txog Kev Nyab Xeeb

    S26; S27; S28

    HS Code:

    2934999090

    Packing Group:

    II

    WGK lub teb chaws Yelemees:

    3

    RIDADR:

    UN 3260 8 / PG 2

    Cov nqe lus yuav raug:

    R14; R34; R51 / 53; R12

    Cov Cai Cov Cai:

    C; N; F +

    daim ntawv pov thawj ntawm kev ntsuam xyuas :

    ProductName:   Mosapride
    Ua li cas:   112885-41-3
    Batch N °: 20100628
    Hnub tim MFG: Lub Rau Hli Ntuj. 28/2010
    Tsom xam Hnub tim : Lub Rau Hli Ntuj. 28/2010

    Tshawb Xyuas Yam

    Quantity Standard

    Kev Tshaj Tawm R

    Tsos

    Dawb los yog dawb crystalline dawb
    hmoov

    Yuav luag dawb crystalline
    hmoov

    Melting point

    153.0 ℃ ~ 157.0 ℃

    155.0 ℃ ~ 156.5 ℃

    Xim ntawm cov kua (DMF)

    Lub teeb daj lossis lub teeb xim av, tsis muaj
    insoluble quav tshuaj

    Conforms

    Hnyav hlau

    15ppm

    <>

    Residue rau ignition

    0.1%

    0.06%

    Poob rau ziab

    0.5%

    0.12%

    Purity (HPLC)

    99.5%

    99.81%

    C onclusion

    Ua raws li kev ua lag luam qauv

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